This DOE-SIM Pro app contains 9 experiment simulators of multi-factored processes that can be used for conducting various experiments to assist in teaching design of experiments (DOE) principles, a key component of Six-Sigma. These simulators can be used in several ways. It can be used by the instructor to generate data from one of the process based on a certain experimental design. Used this way, the student would analyze the data given, develop the appropriate model, and report on the findings. Another way to use the simulators is to ask students to design the experiment for a given process, collect the data, and then analyze the data they have collected. Data can be simulated to illustrate the simple t-test, one factor ANOVA, general ANOVA, 2-level factorial designs, fractional factorial designs, and response surface designs. Other concepts such as replications, blocking, and randomization can also be illustrated using the DOE-SIM Pro app. We also provide a free version named as DOE-SIM that has only three experiment simulators, please search by DOE-SIM.